The Boston Red Sox host the New York Mets in the first of a 3-game interleague matchup on Monday, May 19, 2025. First pitch from Fenway Park is scheduled for 6:45 p.m. EDT; the game will be broadcast on NESN.
The Mets (29-18) are first in the National League East. The Red Sox (23-25) are second in the American League East.
New York is a -130 moneyline favorite, while Boston is a +110 moneyline underdog. The total is 9 (-108/-112).
Read our Mets vs Red Sox prediction and same-game parlay picks below.
Mets vs Red Sox Prediction, Parlay
- New York Mets ML
- Kodai Senga Over 17.5 Outs
Parlay Odds: +144 (DraftKings)
Mets vs Red Sox Odds, Line
Monday, May 19
6:45 p.m. ET
NESN
| Mets Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
|
-1.5 +124 |
9 -108o / -112u |
-130 |
| Red Sox Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
|
+1.5 -148 |
9 -108o / -112u |
+110 |
Mets vs Red Sox Projected Pitchers
| RHP Kodai Senga (NYM) | Stat | RHP Hunter Dobbins (BOS) |
|---|---|---|
| 4-2 | W-L | 2-1 |
| 1.2 | fWAR (FanGraphs) | 0.5 |
| 1.02 / 3.33 | ERA /xERA | 3.90 / 3.63 |
| 2.84 / 4.21 | FIP / xFIP | 3.49 / 3.54 |
| 1.17 | WHIP | 1.30 |
| 13.0% | K-BB% | 16.0% |
| 41.2% | GB% | 44.4% |
| 94 | Stuff+ | 96 |
| 97 | Location+ | 103 |
How To Make Mets vs Red Sox Picks
I’m trusting the road team in this interleague matchup.
New York enters the contest after a disappointing loss to the Yankees on Sunday night.
The Mets hold the advantage on the mound tonight with their ace, Kodai Senga.
Senga has been outstanding this season, with a 1.02 ERA across eight starts.
He has allowed one run in May and should continue his strong pitching tonight.
Hunter Dobbins will toe the rubber for Boston. He has struggled in May with a 4.86 ERA across three starts.
Kodai Senga Over 17.5 Outs
I expect the Mets to get length out of the right-hander tonight.
As mentioned, Senga has allowed one run in May and is currently pitching at an extremely high level.
He has thrown 87 pitches or more in five consecutive starts, which shows the Mets are allowing him to pitch deep into games.
The righty will deliver a high-level start and cash this prop tonight.
Mets vs Red Sox Parlay
- New York Mets ML
- Kodai Senga Over 17.5 Outs
Parlay Odds: +144 (DraftKings)
Mets vs Red Sox Betting Trends
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