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Yankees at Angels odds, picks and predictions

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The New York Yankees (33-20) and the Los Angeles Angels (25-28) play the second game of a 3-game set Tuesday. First pitch from Angel Stadium in Anaheim is scheduled for 9:38 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the Yankees vs. Angels odds and make our expert MLB picks and predictions for the best bets.

Season series: Yankees lead 1-0

The Yankees beat the Angels 5-1 as -190 road favorites in the Monday opener with the Under (9.5) hitting. SS Anthony Volpe cleared the bases with a 3-run double in the fourth inning, while SP Ryan Yarbrough (6 IP, 1 ER, 2 H, 1 BB, 7 K) earned the win to improve to 2-0.

Angels SS Zach Neto led off Monday’s game with a home run to give Los Angeles a 1-0 lead, which held until the fourth inning. The Angels have dropped 3 straight following their 8-game winning streak from May 16-23.

Yankees at Angels projected starters

LHP Carlos Rodón vs. LHP Tyler Anderson

Rodón (6-3, 2.88 ERA) makes his 12th start. He has a 0.96 WHIP, 3.6 BB/9 and 11.0 K/9 in 65 2/3 innings.

  • Last start: Win, 6 IP, 0 ER, 2 H, 2 BB, 8 K in 1-0 home victory vs. Texas Rangers Thursday
  • 2025 road stats: 3-1, 3.19 ERA (31 IP, 11 ER), 0.97 WHIP, 12.2 K/9 in 5 starts
  • 2024 vs. Angels: 1 road start (May 30), win, 6 IP, 3 ER, 3 H, 1 BB, 5 K in 8-3 victory
  • Career vs. Angels: 3-4, 5.21 ERA (38 IP, 22 ER), 1.29 WHIP, 8.8 K/9 in 7 starts

Anderson (2-1, 3.60 ERA) makes his 11th start. He has a 1.24 WHIP, 3.8 BB/9 and 7.0 K/9 in 55 innings.

  • Last start: No-decision, 4 2/3 IP, 5 ER, 7 H, 6 BB, 0 K in 10-5 victory at A’s Thursday
  • 2025 home stats: 1-1, 2.51 ERA (28 2/3 IP, 8 ER), 1.01 WHIP, 7.5 K/9 in 5 starts
  • 2024 vs. Yankees: 1-1, 1.64 ERA (11 IP, 2 ER), 7 H, 7 BB, 11 K in 2 starts
  • Career vs. Yankees: 1-1, 2.25 ERA (16 IP, 4 ER), 12 H, 9 BB, 15 K in 3 starts

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Yankees at Angels odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:32 a.m. ET.

  • Moneyline (ML): Yankees -190 (bet $190 to win $100) | Angels +155 (bet $100 to win $155)
  • Run line (RL)/Against the spread (ATS): Yankees -1.5 (-120) | Angels +1.5 (+100)
  • Over/Under (O/U): 9 (O: -105 | U: -115)

Yankees at Angels picks and predictions

Prediction

Yankees 5, Angels 3

The Yankees (-190) will likely hand Los Angeles its fourth straight loss, but the preferred play is to bet them on the run line at greater odds.

PASS on the ML.

Two of New York’s last 3 games have ended in Yankees wins by at least 4 runs. They’ve scored 5 or more runs in 3 straight contests, while Rodón has allowed just 1 run over 11 innings across his last 2 starts. Conversely, Anderson has surrendered 4 or more runs in back-to-back outings.

BET YANKEES -1.5 (-120).

The Under has hit in each of Rodón’s last 2 starts and in 10 of the Yankees’ last 12 games overall. However, this isn’t an official play, as the Over has cashed in 5 straight outings for Anderson.

LEAN UNDER 9 (-115).

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